"Today, high-resolution nuclear magnetic resonance spectroscopy at the scale of single cells is possible. This opens new industrial applications for this cutting-edge technology."
What is your role in QuantumDiamonds?
My role is to advise and guide the team from the science and technology direction.
You work with NV centers in diamond that can have various applications. What exactly were you researching?
My research group is using NV-centers in diamond for applications in chemistry and life sciences. We currently focus on nuclear magnetic resonance spectroscopy, which typically needs large sample volumes due to its low intrinsic sensitivity. NV-quantum sensors overcome this limitation and allow for nano- to micro NMR spectroscopy within microfluidics, of single cells, thin film materials, or surfaces.
This technology relies on excellent NV-diamonds, which were so far not commercially available. QuantumDiamonds will fill this gap.
Selected works
Micron-scale SABRE-enhanced NV-NMR Spectroscopy.
Arunkumar, N., Bucher, D. B., Turner M., TomHon P., Glenn, D., Lehmkuhl, S., Lukin, M., Park, H., Rosen, M., Theis, T. and Walsworth, R. L. Micron-scale SABRE-enhanced NV-NMR Spectroscopy. PRX Quantum 2, 010305 (2021)
Microfluidic quantum sensing platform for lab-on-a-chip applictions
Allert, R. D., Bruckmaier, F., Neuling, N. R., Freire-Moschovitis, F. A., Liu, K. S., Schrepel, C., ... & Bucher, D. B. (2022). Microfluidic quantum sensing platform for lab-on-a-chip applications. Lab on a Chip.
Quantum diamond spectrometer for nanoscale NMR and ESR spectroscopy.
Bucher, D. B.°, Aude Craik, D. P. L., Backlund, M. P., Turner, M., Glenn, D. R. and Walsworth, R. L°. Quantum diamond spectrometer for nanoscale NMR and ESR spectroscopy. Nature Protocols 14, 2707–2747 (2019)
Surface NMR using quantum sensors in diamond
Liu, K., Henning, A., Heindl M. W., Allert R. D., Bartl J. D., Sharp I. D., Rizzato R., Bucher, D. B.°, Surface NMR using quantum sensors in diamond, PNAS, 119 (5) e2111607119 (2022)
Hyperpolarization-enhanced NMR spectroscopy with femtomole sensitivity using quantum defects in diamond.
Bucher, D. B.°, Glenn, D. R., Park, H., Lukin, M. D., Walsworth, R. L.° Hyperpolarization-enhanced NMR spectroscopy with femtomole sensitivity using quantum defects in diamond. Physical Review X 10, 021053 (2020)
Principes of Nano- and Microscale NMR Spectroscopy with NV-Diamond Sensors.
Bucher, D. B.°. Principes of Nano- and Microscale NMR Spectroscopy with NV-Diamond Sensors. eMagRes 8, 1-8, 2019 ( https://doi.org/10.1002/9780470034590.emrstm1619 )
Advances in nano- and microscale NMR spectroscopy using diamond quantum sensors.
Allert D. R., Briegel K. D., Bucher D. B.°, Advances in nano- and microscale NMR spectroscopy using diamond quantum sensors. Chemical Communications 58, 8165 - 8181 (2022)
UV‐Induced Charge Transfer States in Short Guanosine‐Containing DNA Oligonucleotides.
Kufner, C., Zinth, W., Bucher, D. B.°, UV‐Induced Charge Transfer States in Short Guanosine‐Containing DNA Oligonucleotides. ChemBioChem 21, 1 –6 (2020), selected as "very important paper"
Quantum Logic Enhanced Sensing in Solid-State Spin Ensembles
Arunkumar N.,Olsson K.S., Oon J. T, Hart C., Bucher D.B., Glenn D., Lukin M. D., Park H., Ham D., Walsworth R. L. Quantum Logic Enhanced Sensing in Solid-State Spin Ensembles, arXiv:2203.12501
Unveiling the Zero-Phonon Line of the Boron Vacancy Center by Cavity Enhanced Emission
Qian, C., Villafañe, V., Schalk, M., Astakhov, G. V., Kentsch, U., Helm M., Soubelet, P., Wilson N. P., Rizzato, R., Mohr S., Bucher, D. B., Stier, A. V., Finley, J. J. Unveiling the Zero-Phonon Line of the Boron Vacancy Center by Cavity Enhanced Emission. Nano Letters. 22, 13, 5137–5142 (2022)
Using metal-organic frameworks to confine liquid samples for nanoscale NV-NMR
Liu, K., Ma, X., Rizzato R. Semrau A., Henning, A., Sharp I. D., Fischer R A., Bucher, D. B.°, Using metal-organic frameworks to confine liquid samples for nanoscale NV-NMR, arXiv:2209.05308
Geometry dependence of micron-scale NMR signals on NV-diamond chips.
F. Bruckmaier, K. Briegel, D .B. Bucher° Geometry dependence of micron-scale NMR signals on NV-diamond chips. Journal of Magnetic Resonance Open, 100023 (2021)
Polarization transfer from optically pumped ensembles of NV centers to multinuclear spin baths
Rizzato, R., Bruckmaier, F., Liu K. S., Glaser, S., Bucher, D. B.° Polarization transfer from optically pumped ensembles of NV centers to multinuclear spin baths, Phys. Rev. Applied 17, 024067 (2022)
